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Anti-Obesity Medications Beyond GLP-1s

You'll be able to match non-GLP-1 anti-obesity medications to patient-specific factors like cost, needle aversion, intolerance, and comorbidities.

What this track covers

This track covers the anti-obesity pharmacotherapy landscape outside of GLP-1 receptor agonists, including oral agents, sympathomimetics, and combination products. It focuses on mechanism of action, patient selection, contraindications, and how these agents fit alongside or instead of GLP-1 therapy.

What you will practice

  • Differentiate mechanisms of action across non-GLP-1 anti-obesity drug classes
  • Select an agent based on cost, administration route, or needle aversion
  • Screen for contraindications before starting a sympathomimetic or combination agent
  • Choose an alternative mechanism for a patient who is GLP-1 intolerant
  • Evaluate combination therapy options for a weight-loss plateau

Simulator scenario

A patient with a weight-loss plateau on an oral agent and a history of GLP-1 intolerance who is exploring combination therapy options.

Board question topics

  • Mechanism of action of non-GLP-1 anti-obesity agents
  • Contraindications and precautions by medication class
  • Patient selection for oral versus combination therapy
  • Managing plateaus with multi-mechanism approaches

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