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Tirzepatide Protocols for Weight Loss

You'll be able to evaluate patient candidacy, structure a titration plan, and manage side effects and follow-up for tirzepatide therapy.

What this track covers

This track covers dual GIP/GLP-1 receptor agonism and its metabolic effects, patient selection and contraindications, dosing and titration strategy, and ongoing monitoring for weight management therapy. It's designed for clinicians who prescribe or co-manage patients on incretin-based weight loss agents and want a structured way to reason through protocol decisions.

What you will practice

  • Screen a patient's history for contraindications and comorbidities before initiating therapy
  • Walk through a titration schedule and identify when to hold or slow escalation
  • Recognize and triage common GI side effects versus signs requiring escalation of care
  • Build a monitoring and follow-up cadence for a patient on maintenance dosing
  • Discuss a plan for long-term management, including weight regain risk

Simulator scenario

A simulated follow-up visit with a patient reporting GI side effects during dose escalation, requiring the clinician to decide whether to hold, adjust, or continue titration.

Board question topics

  • Mechanism of dual GIP/GLP-1 receptor agonism
  • Patient selection and contraindications
  • Titration and dose adjustment scenarios
  • Monitoring and long-term management planning

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