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Depression Treatment Optimization

Sharpen your ability to select, optimize, and adjust antidepressant regimens, including strategies for cases that don't respond to first-line treatment.

What this track covers

This track covers the full arc of depression management: screening and severity assessment, first-line agent selection based on patient-specific factors, dose optimization and switching strategies, and approaches to treatment-resistant depression including augmentation. It's built for clinicians who already prescribe or co-manage antidepressants and want a structured way to sharpen decision-making across common and difficult cases.

What you will practice

  • Interpreting PHQ-9 and other severity scores to guide next steps
  • Choosing among first-line antidepressant classes based on comorbidities and side-effect profile
  • Deciding when to optimize dose versus switch agents versus augment
  • Recognizing patterns that suggest treatment-resistant depression
  • Applying measurement-based care to track response over time

Simulator scenario

A patient with persistent depressive symptoms after an adequate trial of a first-line agent, requiring the clinician to decide between optimizing, switching, or augmenting.

Board question topics

  • Differentiating adequate trial from inadequate dosing or duration
  • Augmentation strategy selection in partial responders
  • Recognizing red flags requiring specialist referral
  • Applying measurement-based care tools in follow-up visits

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