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Advanced Lipid Management

You'll be able to select and sequence advanced lipid-lowering therapy, including PCSK9 inhibitors and other non-statin agents, for patients who don't reach LDL goals on statins alone.

What this track covers

This track covers lipid management beyond first-line statin therapy: risk stratification with ASCVD scoring and coronary artery calcium, optimizing statin intensity and managing intolerance, and adding non-statin agents such as PCSK9 inhibitors, bempedoic acid, ezetimibe, and inclisiran. It also addresses special cases like familial hypercholesterolemia, elevated Lp(a), and hypertriglyceridemia.

What you will practice

  • Calculating ASCVD risk and applying risk enhancers to set LDL targets
  • Choosing high-intensity statin regimens and troubleshooting statin intolerance
  • Identifying candidates for PCSK9 inhibitor therapy and navigating prior authorization
  • Sequencing non-statin add-on therapies when LDL goals aren't met
  • Recognizing and managing familial hypercholesterolemia and severe hypertriglyceridemia

Simulator scenario

A patient on high-intensity statin therapy with persistently elevated LDL returns for follow-up, requiring the clinician to reassess risk, address possible statin intolerance, and decide on next-step therapy.

Board question topics

  • ASCVD risk calculation and risk enhancers
  • Statin intensity selection and intolerance management
  • PCSK9 inhibitor and non-statin therapy indications
  • Familial hypercholesterolemia and Lp(a) management

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