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Resistant Hypertension and Secondary Causes

You'll be able to distinguish true resistant hypertension from pseudo-resistance and non-adherence, structure a secondary-cause workup, and reason through combination pharmacotherapy for complex patients.

What this track covers

This track covers the evaluation and management of blood pressure that remains above goal despite multiple agents. It addresses confirming true resistance with proper measurement and adherence checks, screening for secondary causes such as renal artery stenosis, primary aldosteronism, and pheochromocytoma, and adjusting therapy for patients with CKD, heart failure, pregnancy, or advanced age.

What you will practice

  • Differentiate true resistant hypertension from white coat effect and pseudo-resistance
  • Build a stepwise secondary-cause workup based on clinical clues
  • Sequence add-on therapy including mineralocorticoid receptor antagonists
  • Interpret ambulatory blood pressure monitoring patterns, including dipping status
  • Adjust the treatment approach for CKD, heart failure, pregnancy, and elderly patients

Simulator scenario

A patient on three antihypertensive agents with persistently elevated home readings, prompting a workup for secondary causes and adjustment of the regimen.

Board question topics

  • Defining and confirming resistant hypertension
  • Screening tests for secondary hypertension
  • Selecting add-on antihypertensive therapy
  • Ambulatory blood pressure monitoring interpretation

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