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Hematology Fundamentals

You'll be able to interpret a CBC, classify anemias, work up coagulation abnormalities, and reason through anticoagulation decisions with more confidence.

What this track covers

This track covers the core hematology skills clinicians use daily: reading CBC indices and patterns, working up microcytic, macrocytic, and hemolytic anemias, interpreting PT/INR and PTT, and managing anticoagulation and thrombocytopenia. It also covers when transfusion is indicated and how to think through platelet and bleeding disorder workups.

What you will practice

  • Interpret CBC indices and flag patterns that need further workup
  • Differentiate iron deficiency, B12/folate deficiency, anemia of chronic disease, and hemolytic anemia
  • Reason through an elevated PT/INR or PTT and narrow the differential
  • Weigh anticoagulation choices, monitoring needs, and reversal considerations
  • Decide when thrombocytopenia or a bleeding pattern warrants transfusion or further testing

Simulator scenario

A patient presents with fatigue and a low hemoglobin on routine labs, and the clinician must work through the CBC pattern, order the right follow-up tests, and reach a working diagnosis within the visit.

Board question topics

  • CBC index interpretation and anemia classification
  • PT/INR and PTT differentials
  • Anticoagulation monitoring and reversal principles
  • Thrombocytopenia and transfusion decision-making

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