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Interpreting Arterial Blood Gases

You'll be able to work through an ABG systematically to identify the primary acid-base disorder, determine whether compensation is appropriate, and assess oxygenation.

What this track covers

This track covers the core components of arterial blood gas interpretation: pH, pCO2, HCO3, and base excess, along with a stepwise method for identifying respiratory, metabolic, and mixed acid-base disorders. It also addresses oxygenation assessment using PaO2, the A-a gradient, and the P/F ratio, and how these findings connect to clinical decision-making.

What you will practice

  • Apply a consistent step-by-step method to any ABG rather than pattern-matching
  • Distinguish acute from chronic respiratory disorders using expected compensation
  • Differentiate anion gap from non-anion gap metabolic acidosis
  • Identify when an ABG reflects a mixed disorder rather than a single primary process
  • Calculate and interpret the A-a gradient and P/F ratio for oxygenation status

Simulator scenario

A patient with worsening dyspnea and confusion presents with an ABG requiring the clinician to identify a mixed acid-base disorder and decide on next steps within a time-limited scenario.

Board question topics

  • Step-by-step ABG interpretation approach
  • Compensation patterns in respiratory disorders
  • Anion gap versus non-anion gap metabolic acidosis
  • Oxygenation calculations and interpretation

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