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Allergy Testing and Interpretation

Build the skills to select the right allergy test, perform it correctly, and interpret results in the context of a patient's history.

What this track covers

This track covers the diagnostic workup for suspected IgE-mediated allergy, including skin prick and intradermal testing, serum-specific and total IgE, and component-resolved diagnostics. It emphasizes matching the test to the clinical question, distinguishing sensitization from clinically relevant allergy, and applying results to food, drug, venom, and environmental allergy scenarios.

What you will practice

  • Choose between skin testing and serum IgE based on the clinical scenario
  • Interpret wheal-and-flare results alongside positive and negative controls
  • Differentiate primary sensitization from cross-reactivity using component-resolved data
  • Decide when intradermal testing is appropriate for drug or venom allergy
  • Correlate test results with history before recommending an elimination diet or food challenge

Simulator scenario

A patient with recurrent hives after eating tree nuts presents for evaluation, requiring the clinician to select appropriate testing, interpret component-resolved results, and decide whether an oral food challenge is warranted.

Board question topics

  • Interpreting skin prick test controls and results
  • Serum total vs specific IgE clinical significance
  • Component-resolved diagnostics and cross-reactivity
  • Testing strategy for suspected food allergy

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